The major focus of our research is to understand the developmental mechanisms underlying the formation of the vertebrate peripheral nervous system, with a particular emphasis on the formation of the enteric nervous system. Using zebrafish as a model, we aim to examine the genetic, molecular and cellular basis of the signals that direct peripheral nervous system development and function. Increasing our understanding of how the nervous system develops and is maintained can help further our knowledge of how alterations in these processes may lead to nervous system dysfunction and disease.
